They include notable first-team names like Petr Cech, Stephan Lichsteiner, Danny Welbeck and Aaron Ramsey.
Cech is set to return to Chelsea, where he has been offered a Sporting Director role, while Ramsey has already agreed a lucrative deal with Juventus.
A club statement on Friday, read: “Our thanks and best wishes go to the following players whose contracts end with us on June 30:
“Cohen Bramall, Petr Cech, Charlie Gilmour, Stephan Lichtsteiner, Julio Pleguezuelo, Aaron Ramsey, Danny Welbeck.
“We thank them all for their contributions to the club and we wish them every future success.”